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Cysts are resistant forms
and are responsible for transmission
of giardiasis. Both
cysts and trophozoites can
be found in the feces (diagnostic
stages) .
The cysts are hardy, can survive
several months in cold water.
Infection occurs by the ingestion
of cysts in contaminated water,
food, or by the fecal-oral
route (hands or fomites) .
In the small intestine, excystation
releases trophozoites (each
cyst produces two trophozoites)
.
Trophozoites multiply by longitudinal
binary fission remaining in
the lumen of the proximal
small bowel where they can
be free or attached to the
mucosa by a ventral sucking
disk .
Encystation occurs as the
parasites transit toward the
colon. The cyst is the
stage found most commonly
in non-diarrheal feces .
Because the cysts are infectious
when passed in the stool or
shortly afterward, person-to-person
transmission is possible.
While animals are infected
with Giardia, their
importance as a reservoir
is unclear.
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