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Trichinellosis is
acquired by ingesting
meat containing cysts
(encysted larvae)
of Trichinella.
After exposure to
gastric acid and pepsin,
the larvae are released
from
the cysts and invade
the small bowel mucosa
where they develop
into adult worms
(female 2.2 mm in
length, males 1.2
mm; life span in the
small bowel: 4 weeks).
After 1 week, the
females release larvae
that migrate to the
striated muscles where
they encyst .
Trichinella pseudospiralis,
however, does not
encyst. Encystment
is completed in 4
to 5 weeks and the
encysted larvae may
remain viable for
several years.
Ingestion of the encysted
larvae perpetuates
the cycle. Rats
and rodents are primarily
responsible for maintaining
the endemicity of
this infection.
Carnivorous/omnivorous
animals, such as pigs
or bears, feed on
infected rodents or
meat from other animals.
Different animal hosts
are implicated in
the life cycle of
the different species
of Trichinella.
Humans are accidentally
infected when eating
improperly processed
meat of these carnivorous
animals (or eating
food contaminated
with such meat).
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